What is Platelet-Rich Plasma?
Platelet-Rich Plasma is a concentrated portion of your own blood that contained platelets and growth factor that aid in repairing damaged tissue in the body. Platelet-Rich Plasma is injected to the site of injury to accelerate and assist in the healing process.
Growth factors contained in PRP:
Platelet derived growth factor PDGF -Enhances collagen synthesis, proliferation of bone cells, fibroblast chemotaxis and proliferative activity, macrophage activation
Transforming growth factor ß TGF-ß -Enhances synthesis of type I collagen, promotes angiogenesis, stimulates chemotaxis of immune cells, inhibits osteoclast formation and bone resorption
Vascular endothelial growth factor VEGF -Stimulates angiogenesis, migration and mitosis of endothelial cells, increases permeability of the vessels, stimulates chemotaxis of macrophages and neutrophils
Epidermal growth factor EGF -Stimulates cellular proliferation, differentiation of epithelial cells, promotes cytokine secretion by mesenchymal and epithelial cells
Insulin-like growth factor IGF -Promotes cell growth, differentiation, recruitment in bone, blood vessel, skin and other tissues, stimulates collagen synthesis together with PDGF
Fibroblast growth factor FGF -Promotes proliferation of mesenchymal cells, chondrocytes and osteoblasts, stimulates the growth and differentiation of chondrocytes and osteoblast
Is PRP right for me?
PRP may be a good option if you have exhausted conservative options and are not yet prepared for surgery. Discussing your treatment options may help you decide when and if PRP is the right treatment option for you.